Ankylosing Spondylitis Ankylosing Spondylitis

Ankylosing Spondylitis

The prototype of the spondyloarthritis group of diseases is ankylosing spondylitis. Its main symptom is back pain of an inflammatory character. Usually, the first symptoms begin at the age of 20s and are more common and serious in men than in women. In addition to the axial system, peripheral joints, eyes, intestines and skin may also be affected by the disease. It is a common disease (about 0.5 percent) all over the world and in our country. Although there is no specific laboratory test, conventional radiographs and magnetic resonance imaging are important for diagnosis. There is substantial evidence of genetic predisposition and its close association with HLA-B27 has been described.

In studies conducted in our country, the incidence of spondyloarthritis was found to be approximately 1 percent and the incidence of ankylosing spondylitis was found to be approximately 0.5 percent. This incidence is similar to that in other countries.

The male/female incidence is reported to be 2-3:1. Men have more serious spine and joint involvements and functional limitations.

Ref: Prevention and Control of Musculoskeletal System Diseases Program of Türkiye (2015-2020).